Effect of PeakATP on Mood, Reaction Time and Cognition

Completed · Not applicable · Has a placebo group

Conditions studied: Cognitive Change, Mood

In brief

Oral ATP disodium (adenosine 5'- triphosphate disodium) is a commercially available product available alone and as a constituent in a number of sports supplements that is purported to maintain ATP levels and improve performance during high-intensity exercise. Acute deficits in cognitive performance have also been reported in both young adults and children following high-intensity exercise; however, the effects of supplemental ATP on cognitive performance has not been studied. Goals: 1. To investigate the effect of ATP supplementation versus. placebo on mood, reaction time and cognitive performance before and after an acute bout of fatiguing exercise. 2. To investigate the effect of ATP supplementation versus. placebo on anaerobic performance.

Key facts

Study ID

NCT05100589

Run by

University of Central Florida

People needed

35

Starts

2021-10-06

Expected to finish

2022-04-19

Last updated by the study team

2022-08-08

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy, and ready for physical activity as determined by physical activity readiness questionnaire (PAR-Q+) and medical history questionnaire (MHQ)
• Participants will be required to be recreationally-active (defined according to the American College of Sports Medicine (ACSM) standards of at least 150 minutes exercise per week)
• Participants must currently not be taking and be willing to abstain from creatine or beta-alanine supplementation or be willing to complete a 4-week wash-out period prior to enrolling if taking creatine or beta-alanine and be willing to abstain from supplementing with wither for the duration of the study. This will be verbally confirmed at the beginning of each visit.
• Participant understands the study procedures and signs forms providing informed consent to participate in the study.

You may not qualify if…

• Individual does not provide consent to participate in this study.
• Inability to perform physical exercise (determined by MHQ and PAR Q+). That is Answering "Yes" to any question on the PAR-Q +, or having a pre-existing condition such as musculoskeletal injury, back pain, chronic pain etc. that the investigative team perceives will prevent a participant from safely completing the protocol.
• Not currently participating in at least 150 minutes of physical activity per week.
• Currently taking any performance-enhancing drug (determined from health and activity questionnaire)
• Currently taking a nutritional supplement known to improve anerobic performance that requires a wash-out period (e.g., creatine, beta-alanine) and are not willing to undergo a 4-week wash-out period prior to participating.
• Regularly taking any type of prescription or over-the-counter medication, or having any chronic illnesses, which require medical care
• Current known pregnancy

Where it is running

• Kinesiology Research Labs — Orlando, Florida, United States

Full record on ClinicalTrials.gov

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