The CARMA Technique Study

Recruiting now · Not applicable

Conditions studied: Colonic Polyp, Colonic Sessile Serrated Lesion

In brief

Colonoscopic removal of polyps is an important and well-established tool in the prevention of colorectal cancers. However, high polyp recurrence rates after endoscopic resection, with resultant development of interval cancers, remains a problem; this most commonly stems from unrecognised incomplete polyp resection. Thus, a standardised endoscopic technique is needed that will allow endoscopists to consistently achieve a clear margin of resection. The investigators believe the Cap Assisted Resection Margin Assessment (CARMA) technique will address this problem. This novel technique focuses on a standardised assessment of the resection margin after endoscopic polypectomy utilising available standard high-definition video endoscopes with imaging features including narrow band imaging (NBI) and magnification endoscopy.

Key facts

Study ID

NCT05099432

Run by

Princess Alexandra Hospital, Brisbane, Australia

People needed

60

Starts

2021-11-01

Expected to finish

2026-11-01

Last updated by the study team

2021-11-15

Who can join

Age: 16 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• any polypectomy (though only a maximum of two polyps from one individual participant)

You may not qualify if…

• polyps less than 10mm which were resected under endoscopic view with a definite > 1mm clear margin
• scar site recurrence polyps
• polyps with endoscopic evidence of invasion
• pedunculated polyps
• pseudopolyps
• participants who will not be available for follow up endoscopy

Where it is running

• Princess Alexandra Hospital — Woolloongabba, Queensland, Australia (enrolling)

Full record on ClinicalTrials.gov

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