Neural Mechanisms for Reducing Interference During Episodic Memory Formation
Enrolling by invitation · Not applicable
Conditions studied: Behavior
In brief
Healthy individuals from the University of Oregon and surrounding community will be recruited for participation in behavioral, fMRI and eye tracking experiments that investigate human memory. Recruitment will involve emails, flyers, and local advertisements. Individuals between the ages of 18-80 (or 18-35 for some studies) will be eligible. The broad objective of the research is to understand how humans form distinct memories for similar experiences. Experimental sessions will involve studying and trying to remember various images (e.g., images of natural scenes). The intervention will involve manipulating the similarity and/or learning protocol for the studied images. Outcome measures will include (a) behavioral measures of memory, and/or (b) fMRI measures of hemodynamic activity, and/or (c) eye tracking measures of gaze direction. Experimental sessions will last approximately 1-3 hours.
Key facts
- Study ID
- NCT05092100
- Run by
- University of Oregon
- People needed
- 737
- Starts
- 2021-09-29
- Expected to finish
- 2026-01-01
- Last updated by the study team
- 2024-09-19
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Participants in behavioral studies must be:
- healthy and between the ages of 18-35 years old
- native English speakers
- right-handed.
- Participants in fMRI studies must be:
- healthy and between the ages of 18-80 years old
- native English speakers
- right-handed.
You may not qualify if…
- For behavioral studies:
- Potential participants will be informed that use of psychoactive drugs, mental health disorders, and chronic or temporary sleep deficits (an average of less than 6 hours of sleep over the past month or less than 4 hours of sleep the night prior to the experimental session) are reasons for exclusion because of the potential influence on cognitive functioning.
- For fMRI studies:
- For some sub-studies, individuals older than age 35 will be excluded because of potential differences in cognitive and brain function across age groups that are beyond the scope of the proposed studies.
- Individuals will be informed that use of psychoactive drugs, mental health disorders, and chronic or temporary sleep deficits (an average of less than 6 hours of sleep over the past month or less than 4 hours of sleep the night prior to the experimental session) are reasons for exclusion because of the potential influence on cognitive functioning.
Where it is running
- University of Oregon — Eugene, Oregon, United States
Full record on ClinicalTrials.gov
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