Cryotherapy in the Treatment of Desmoid Tumors

Recruiting now · Not applicable

Conditions studied: Desmoid

In brief

Desmoid tumor is a benign neoplasm with an unpredictable course and a high rate of local recurrence if treated surgically. Therefore, over time the surgical approach has become conservative, preferring simple observation or medical therapy in case of disease progression through the use of hormonal therapy and low-dose chemotherapy. Since this neoplasm remains benign, our study aims to avoid chemotherapy in patients usually young through the use of a minimally invasive treatment such as cryotherapy.

Key facts

Study ID

NCT05091255

Run by

Istituto Ortopedico Rizzoli

People needed

94

Starts

2021-05-20

Expected to finish

2027-01-01

Last updated by the study team

2025-08-01

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• histologic diagnosis of desmoid tumors
• age > 18 years
• abdominal and extra-abdominal desmoid tumors

You may not qualify if…

• contraindication to the procedure by the interventional radiologist in terms of tumor proximity to neurologic/vascular structures
• retroperitoneal desmoid tumors
• age < 18 years

Where it is running

• IRCCS Itituto Ortopedico Rizzoli — Bologna, BO, Italy (enrolling)

Full record on ClinicalTrials.gov

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