Telephone-Based Support Programs for People With Epilepsy

Recruiting now · Not applicable

Conditions studied: Epilepsy

In brief

This is a two-arm randomized controlled trial to compare telephone-based depression self-management (UPLIFT) to telephone-based support groups (BOOST). A sample of 120 English- and Spanish-speaking people with epilepsy (PWE) with elevated depressive symptoms will be enrolled. Both interventions are 8-week programs delivered in one-hour weekly sessions to groups of about 6 participants. Changes in depressive symptoms, quality of life and seizures will be assessed over 12 months. The trial will also examine mediators and moderators of treatment effects.

Key facts

Study ID

NCT05082181

Run by

NYU Langone Health

People needed

120

Starts

2021-11-09

Expected to finish

2027-08-31

Last updated by the study team

2026-02-17

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• adult (≥18 years of age);
• diagnosed with epilepsy for at least one year;
• fluent in English or Spanish;
• elevated depressive symptoms (PHQ-9 score ≥10);
• willing to participate in audiotaped group telephone sessions

You may not qualify if…

• severe depressive symptoms (PHQ-9 ≥20);
• active suicidal ideation (PHQ-9 item #9 ≥1 or otherwise reported during screening);
• active psychotic disorder (psychiatric diagnosis or antipsychotic medications in the EHR);
• significant cognitive impairment (indicated in EHR or evident during screening)

Where it is running

• NYU Langone Health — New York, New York, United States (enrolling)

Full record on ClinicalTrials.gov

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