Family History and Cancer Risk Study

Completed

Conditions studied: Neoplastic Syndromes, Hereditary, Comparative Effectiveness Research

In brief

Investigators from Vanderbilt University Medical Center (VUMC), Duke University, and Meharry Medical College (MMC) are collaborating on a family health history study to deploy a family health history (FHH) platform, MeTree. Recruited participants will complete surveys, the MeTree questionnaire, and MeTree will determine the participant's cancer risk based on current guidelines. The study team will offer genetic counseling to high-risk participants. Investigators will track participant outcomes and behaviors from the use of MeTree to determine the efficiency of the use of MeTree compared to completion of pedigrees in clinic.

Key facts

Study ID

NCT05079334

Run by

Vanderbilt University Medical Center

People needed

1847

Starts

2022-01-01

Expected to finish

2025-09-01

Last updated by the study team

2026-06-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Receiving care at sites included in study
• Able to read and communicate in English
• Willing to use the Internet
• Currently enrolled in the patient portal, or willing to enroll (VUMC-specific)

You may not qualify if…

• Non-study site patient
• Diagnosed with a terminal illness
• Unable to speak/read English
• Unable/unwilling to use the Internet
• Previous genetic testing and/or counseling from the VUMC Hereditary Cancer Clinic

Where it is running

• Meharry Medical College — Nashville, Tennessee, United States
• Vanderbilt University Medical Center — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

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