Study of Magrolimab Versus Placebo in Combination With Venetoclax and Azacitidine in Participants With Acute Myeloid Leukemia
Stopped early · Phase 3 · Has a placebo group
Conditions studied: Acute Myeloid Leukemia
In brief
The goal of this clinical study is to compare the study drugs, magrolimab + venetoclax + azacitidine, versus placebo + venetoclax + azacitidine in participants with untreated acute myeloid leukemia (AML) who are not able to have chemotherapy.
Key facts
- Study ID
- NCT05079230
- Run by
- Gilead Sciences
- People needed
- 378
- Starts
- 2022-07-07
- Expected to finish
- 2024-04-11
- Last updated by the study team
- 2025-04-04
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- City of Hope (City of Hope National Medical Center, City of Hope Medical Center) — Duarte, California, United States
- Community Cancer Institute — Fresno, California, United States
- UC Irvine Health- Chao Family Comprehensive Cancer Center — Orange, California, United States
- Baptist MD Anderson Cancer Center — Jacksonville, Florida, United States
- Moffitt Cancer Center — Tampa, Florida, United States
- Loyola University Medical Center — Maywood, Illinois, United States
- Parkview Research Center — Fort Wayne, Indiana, United States
- Indiana Blood and Marrow Transplantation - Clinic — Indianapolis, Indiana, United States
- The University of Iowa Hospitals and Clinics — Iowa City, Iowa, United States
- University of Maryland, Greenebaum Comprehensive Cancer Center — Baltimore, Maryland, United States
- University of Massachusetts Worcester — Worcester, Massachusetts, United States
- MidAmerica Division, Inc., c/o Research Medical Center — Kansas City, Missouri, United States
- SSM Health Saint Louis University Hospital — St Louis, Missouri, United States
- John Theurer Cancer Center at Hackensack University Medical Center — Hackensack, New Jersey, United States
- Rutgers Cancer Institute of New Jersey — New Brunswick, New Jersey, United States
- New York-Presbyterian/Weill Cornell Medical Center — New York, New York, United States
- Icahn School of Medicine at Mount Sinai and The Mount Sinai Hospital — New York, New York, United States
- University of Rochester Medical Center — Rochester, New York, United States
- UNC Hospitals, The University of North Carolina at Chapel Hill — Chapel Hill, North Carolina, United States
- Novant Health Cancer Institute Hematology- Charlotte — Charlotte, North Carolina, United States
- Novant Health Cancer Institute Hematology - Forsyth — Winston-Salem, North Carolina, United States
- Wake Forest Baptist Health — Winston-Salem, North Carolina, United States
- University Hospitals Cleveland Medical Center — Cleveland, Ohio, United States
- Cleveland Clinic Foundation — Cleveland, Ohio, United States
- University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
Full record on ClinicalTrials.gov
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