CYP2C19 Variants and Limonene Metabolism

Recruiting now · Not applicable

Conditions studied: CYP2C19 Genetic Variants

In brief

The investigators will examine whether a non-invasive screening tool for CYP2C19 genetic variants can be developed by measuring limonene metabolism.

Key facts

Study ID

NCT05078723

Run by

Stanford University

People needed

20

Starts

2021-10-30

Expected to finish

2026-12-01

Last updated by the study team

2024-12-16

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age range: Greater than 18 years and less than 45 years.
• Gender: Male or Female
• Ethnicities: East Asian

You may not qualify if…

• Pregnant and/or Breastfeeding
• previous allergic reaction to limonene, citrus fruits, bovine gelatin, glycerin
• past medical history of cerebrovascular or cardiovascular disease
• veganism
• history of chest pain or shortness of breath in the past month
• certain medications that are CYP2C19 substrates or CYP2C19 inhibitors
• Non-East Asian descent
• age less than 18 y.o or age greater than 45 y.o

Where it is running

• Stanford School of Medicine — Stanford, California, United States (enrolling)

Full record on ClinicalTrials.gov

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