Re-assessment of Appendicitis Evaluation During Laparoscopic Appendectomy, Peritoneal Irrigation During Laparoscopic Appendectomy Does the Grade of Contamination Matter?
Recruiting now
Conditions studied: Appendicitis, Appendectomy
In brief
Type: prospective observational multicenter trial. Population of interest: adult patients undergoing laparoscopic appendectomy for acute appendicitis. Hypothesis : laparoscopic lavage during laparoscopic appendectomy is a practice that should be used in selected patients according to the intraperitoneal grade of contamination and grade of appendicitis. Nonregulated use of laparoscopic lavage cannot be considered superior to suction only considering recent evidence. Few RCT available addressing this issue are available, but any with a high methodological quality. Aim: The aim of this study is to investigate the impact of laparoscopic lavage during laparoscopic appendectomy on the postoperative incidence of intrabdominal abscesses, stratifying patients in different clusters according to a defined classification considering the intraperitoneal contamination and grade of appendicitis.
Key facts
- Study ID
- NCT05075252
- Run by
- Niguarda Hospital
- People needed
- 1067
- Starts
- 2019-10-01
- Expected to finish
- 2027-09-30
- Last updated by the study team
- 2026-04-16
Who can join
Age: 18 and older, up to 69. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients between 18 and 69 years old
- Surgical laparoscopic approach for AA
- Intra-operative and histological diagnosis of AA
You may not qualify if…
- Patients < 18 years old or > 69 years old
- Previous appendectomy
- Previous appendicitis treated conservatively
- Open approach for surgery or intra-operative conversion
- Co-existence of other intra-abdominal infections (IAI)
- Patients with immunodeficiency
- Patients treated with steroid, immunosuppressant, or CHT within previous 6 months
Where it is running
- ASST GOM Niguarda — Milan, Italy (enrolling)
Full record on ClinicalTrials.gov
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