Early Ageing During Therapy in AYA Cancer Patients

Recruiting now

Conditions studied: Cancer, Leukemia, Hodgkin Lymphoma, Testicular Cancer, Osteosarcoma, Ewing Sarcoma, Breast Cancer, Cervical Cancer

In brief

Longitudinal cohort study; measurements before start of systemic therapy and one year later.

Key facts

Study ID

NCT05062707

Run by

University Medical Center Groningen

People needed

120

Starts

2022-02-10

Expected to finish

2025-07-01

Last updated by the study team

2025-05-13

Who can join

Age: 18 and older, up to 39. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Aged 18-39 years at cancer diagnosis
• Having a histologically and/or cytologically confirmed cancer diagnosis, including leukemia, (non-)Hodgkin lymphoma, testicular cancer, osteosarcoma, Ewing sarcoma, breast cancer, and cervical cancer.
• Scheduled to start systemic therapy with curative intent. Allowed treatments (concurrent or sequential) are: surgery, radiotherapy, chemotherapy, antibodies.

You may not qualify if…

• patients who are not able to understand the patient information letter and informed consent form
• patients who will be treated with immune checkpoint inhibitors or targeted therapy with inhibitors of angiogenesis
• patients who have been treated with systemic therapy or radiotherapy for a previous malignancy (exceptions: in situ carcinoma of the cervix or uterus and adequately treated basal and squamous cell carcinoma of the skin).

Where it is running

• University Medical Center Groningen — Groningen, Netherlands (enrolling)

Full record on ClinicalTrials.gov

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