ICCRT vs. CRT for Locally Advanced Nasopharyngeal Carcinoma

Recruiting now · Phase 3

Conditions studied: Locally Advanced Nasopharyngeal Carcinoma

In brief

This trial is a multi-center phase III clinical trial. The purpose of this trial is to explore whether concurrent chemoradiotherapy is not inferior to induction chemotherapy combined with concurrent chemoradiotherapy in patients with locally advanced nasopharyngeal carcinoma.

Key facts

Study ID

NCT05062005

Run by

First Affiliated Hospital, Sun Yat-Sen University

People needed

447

Starts

2021-09-22

Expected to finish

2027-08-31

Last updated by the study team

2021-09-30

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18-65 years old;
• Pathologically confirmed non-keratinizing nasopharyngeal carcinoma;
• Stage T3-4N0-1 (according to the UICC/AJCC 8th);
• No distant metastasis;
• Have not received anti-cancer treatment in the past;
• ECOG (Eastern Cooperative Oncology Group of the United States): 0-1;
• Adequate hematologic, hepatic and renal function.

You may not qualify if…

• The purpose of treatment is palliative;
• Diagnosed with other malignant tumors at the same time;
• Malignant tumor history;
• Pregnancy or breastfeeding, or expect to become pregnant during the clinical trial period;
• Combined serious illness.

Where it is running

• The First Affiliated Hospital of Sun Yat-sen University — Guangzhou, Guangdong, China (enrolling)

Full record on ClinicalTrials.gov

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