Pilot Study of Pancreatic Cancer Screening
Recruiting now
Conditions studied: Pancreatic Carcinoma
In brief
This study investigates how often abnormal findings from routine magnetic resonance imaging occur in people with genetic mutations in BReast CAncer gene. (BRCA), ataxia telangiectasia mutated gene (ATM), or PALB2 screened for pancreatic cancer. This study may lead to a greater understanding of cancer and potentially, improvements in cancer screening and treatment.
Key facts
- Study ID
- NCT05058846
- Run by
- University of California, San Francisco
- People needed
- 250
- Starts
- 2022-01-20
- Expected to finish
- 2032-01-31
- Last updated by the study team
- 2025-05-02
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Ability to provide consent and willing, and able to comply with study procedures Ability to read and speak English
- GROUP I:
- Documentation of pathogenic or likely pathogenic germline BRCA 1 and 2, ATM or PALB2 germline genetic mutation
- No strong family history of pancreatic cancer (defined as having >= 1 first-degree or second-degree relative with a history of pancreatic cancer)
- Age >= 50 years old at time of consent.
- GROUP II:
- Documentation of pathogenic or likely pathogenic germline BRCA 1 and 2, ATM, or PALB2 germline genetic mutation
- Has strong family history of pancreatic cancer (defined as having >= 1 first-degree or second-degree relative with a history of pancreatic cancer)
- Age >= 18 years old at time of consent (screening generally begins 10 years prior to the earliest pancreatic cancer in the family)
You may not qualify if…
- Prior or active pancreatic cancer.
- Pregnant women are excluded from this study because effects of an MRI on developing fetus is unknown.
Where it is running
- University of California San Francisco — San Francisco, California, United States (enrolling)
Full record on ClinicalTrials.gov
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