Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression

Recruiting now · Phase 3 · Has a placebo group

Conditions studied: Opioid Use, Lumbar Spinal Stenosis, Pain, Postoperative, Pain, Back

In brief

This study seeks to evaluate the impact of intra-operative topical epidural steroid usage in patients undergoing 1-2 level lumbar laminectomy. The study will examine post-operative opioid usage, length of stay, return to work, and patient reported outcomes following these procedures.

Key facts

Study ID

NCT05058287

Run by

Hospital for Special Surgery, New York

People needed

150

Starts

2021-11-05

Expected to finish

2026-12-31

Last updated by the study team

2026-04-28

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients scheduled to undergo 1 to 2 level laminectomy
• Between the ages of 18-85

You may not qualify if…

• Minimally invasive surgery
• Prior daily opioid usage within 6 months.
• Use of concomitant procedures such as spinal fusion, revision procedure at the same level.
• History of a chronic pain syndrome, uncontrolled diabetes defined as A1C > 6.5, immunocompromised condition such as active cancer treatment, history of transplant, benign prostatic hyperplasia or history of urinary retention, and other conditions which require chronic steroid therapy or immunosuppressants.
• Non-English speakers
• Patients allergic to Depo-Medrol and/or glucocorticoids, or other steroids

Where it is running

• Hospital for Special Surgery — New York, New York, United States (enrolling)

Full record on ClinicalTrials.gov

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