Navigate - Improving Survival and Quality of Life in Vulnerable Lung Cancer Patients

Recruiting now · Not applicable

Conditions studied: Lung Cancer

In brief

Half of patients with lung cancer face a limited life span of one-year survival, which is characterized by severe physical and psychological symptoms. Differences in stage, comorbidity but also treatment may explain a large proportion of the social inequality in lung cancer survival. Some vulnerable patients may not receive first line treatment as planned either due to poor performance status or if they are not able to adhere to treatment appointments. Knowing how to navigate the health system may be a barrier preventing vulnerable patients in receiving optimal treatment. The primary aim of this randomised, controlled trial is to test whether a nurse-led individually tailored program including systematic screening of symptoms using PROs and a physical training program will significantly improve a composite outcome of survival and quality of life as the primary outcome among vulnerable lung cancer patients compared with standard care. Secondary outcomes include adherence to cancer treatment, symptom burden and overall survival.

Key facts

Study ID

NCT05053997

Run by

Zealand University Hospital

People needed

250

Starts

2022-03-01

Expected to finish

2026-12-31

Last updated by the study team

2025-12-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years of age
• Diagnosed with NSCLC at all stages regardless of treatment intension at the participating departments
• Performance status ≤ 2
• Vulnerable according to pre-defined criteria

You may not qualify if…

• Severe untreated psychiatric disorder (e.g. psychosis) or cognitive problems (e.g. dementia) preventing informed consent
• Not able to receive treatment
• Not able to read and understand Danish -

Where it is running

• Aalborg University Hospital — Aalborg, Denmark (enrolling)
• Gødstrup Hospital — Herning, Denmark (enrolling)
• Odense University Hospital — Odense, Denmark (enrolling)
• Zealand University Hospital — Roskilde, Denmark (enrolling)
• Sønderborg Sygehus — Sønderborg, Denmark (enrolling)
• Vejle Sygehus — Vejle, Denmark (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.