A Study of TRS01 in Subjects With Active Non-infectious Anterior Uveitis Including Subjects With Uveitic Glaucoma

Completed · Phase 3

Conditions studied: Non-infectious Anterior Uveitis, Uveitic Glaucoma

In brief

The primary objective of this study is to evaluate the efficacy and safety of TRS01 eye drops compared to active comparator in subjects with active non-infectious anterior uveitis with or without uveitic glaucoma

Key facts

Study ID

NCT05042609

Run by

Tarsier Pharma

People needed

142

Starts

2021-09-20

Expected to finish

2023-06-29

Last updated by the study team

2026-05-20

Who can join

Age: any, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• At sites in the US: Male or female up to and including 75 years of age (including all pediatric age groups). At sites in the Europe: Male or female between 18 and 70 years of age, inclusive.
• Diagnosed with active non-infectious anterior uveitis with anterior chamber cell Grade 2 (6-15 cells) or Grade 3 (16-30 cells) in the study eye that are without any treatment or with Stable Medical Therapy requiring further treatment.
• Have Best Corrected Visual Acuity (BCVA) vision ≥ 65 letters in the non-study eye using Early Treatment Diabetic Retinopathy Study (ETDRS).

You may not qualify if…

• Pregnant or breastfeeding females or females.
• History of or active significant ocular disease in either eye.
• Uncontrolled intraocular pressure (IOP; defined as >27mmHg) or narrow angle glaucoma in either eye and/or are at risk of angle closure with dilating.
• Poor posterior view due to limitation of dilation or media opacity that limits ability to examine the posterior segment.
• Cancer or melanoma that is actively treated with immunotherapy.
• Certain clinically significant systemic diseases or conditions.
• Receiving specific medication/interventions as specified per protocol.

Where it is running

• La Jolla — La Jolla, California, United States
• Los Angeles — Los Angeles, California, United States
• Los Angeles 2 — Los Angeles, California, United States
• Aurora — Aurora, Colorado, United States
• Lakewood — Lakewood, Colorado, United States
• Jacksonville — Jacksonville, Florida, United States
• Winter Haven — Winter Haven, Florida, United States
• Marietta — Marietta, Georgia, United States
• Boston — Boston, Massachusetts, United States
• Waltham — Waltham, Massachusetts, United States
• Washington, MO — Washington, Missouri, United States
• Palisades Park — Palisades Park, New Jersey, United States
• Winston-Salem — Winston-Salem, North Carolina, United States
• Nashville — Nashville, Tennessee, United States
• Austin — Austin, Texas, United States
• Plano — Plano, Texas, United States
• San Antonio 2 — San Antonio, Texas, United States
• San Antonio — San Antonio, Texas, United States
• Norfolk — Norfolk, Virginia, United States
• Dijon — Dijon, France
• Lyon — Lyon, France
• Nantes — Nantes, France
• Paris — Paris, France
• Paris — Paris, France
• Bonn — Bonn, Germany

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.