Efficacy at One Year of Combined Injections of Plasma Rich in Platelets and Hyaluronic Acid in Knee Osteoarthritis

Recruiting now

Conditions studied: Knee Osteoarthritis, Hyaluronic Acid, Platelet Rich Plasma

In brief

The French Society of Rheumatology cannot rule on the value of intra-articular injections of PRP due to the lack of hindsight and insufficient data. In fact, the injection protocols are very heterogeneous in terms of preparation method, the presence or not of leukocytes, the number of centrifugations, the volume injected, the ultrasound guidance, which makes it difficult to analyze the literature. The investigator objective is therefore to evaluate the effectiveness of combined injections of PRP and hyaluronic acid.

Key facts

Study ID

NCT05039463

Run by

Centre Hospitalier Universitaire, Amiens

People needed

100

Starts

2021-08-16

Expected to finish

2026-06-01

Last updated by the study team

2026-06-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• age : > 18 years old
• Patients benefiting, in the context of knee osteoarthritis, from viscosupplementation alone or from two injections of PRP, in combination with HA, at the Amiens University Hospital.

You may not qualify if…

• Patient refusal to use the data
• Language barrier
• Age less than 18 years old.

Where it is running

• CHU Amiens — Amiens, France (enrolling)

Full record on ClinicalTrials.gov

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