Telehealth 2.0: Evaluating Effectiveness and Engagement Strategies for CPT-Text for PTSD

Running, not enrolling · Not applicable

Conditions studied: Posttraumatic Stress Disorder

In brief

There is a pressing need to increase capacity to treat PTSD related to or exacerbated by the COVID-19 pandemic. Texting-based therapy holds promise to increase capacity and reduce barriers to delivering evidence-based treatments (EBTs), but ongoing engagement in digital mental health interventions is low. This study will compare a texting-based EBT for PTSD to culturally-informed texting-based treatment for PTSD as usual, and it will also compare a unique incentive strategy to typical platform reminders aimed to prevent early discontinuation in therapy. This online study is open to individuals who live in 18 different states.

Key facts

Study ID

NCT05037175

Run by

Stanford University

People needed

360

Starts

2022-03-22

Expected to finish

2026-06-29

Last updated by the study team

2025-08-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Over the age of 18 residing in the United States
• Criterion A event measured by the Life Events Checklist for DSM-5 (LEC-5)
• Significant symptoms of PTSD as evidenced by a score of 33 or above on the PCL-5
• PTSD symptoms that began or increased during the COVID pandemic (per self-report)
• Registered/registering on Talkspace for messaging-based therapy
• Ownership of a personal device for texting
• Residence in a state with therapist capacity on the Talkspace platform

You may not qualify if…

• Acute risk for suicidal thoughts and/or behaviors measured by the Columbia Suicide Severity Rating Scale Lifetime-Recent Screen
• Psychosis or substance abuse that requires prioritization of treatment and/or higher level of care

Where it is running

• Stanford University — Palo Alto, California, United States
• Talkspace LLC — New York, New York, United States
• University of Texas Health Sciences Center at San Antonio — San Antonio, Texas, United States

Full record on ClinicalTrials.gov

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