Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise
Recruiting now
Conditions studied: Chronic Lung Disease, Chronic Obstructive Pulmonary Disease, Acute Lymphoblastic Leukemia, Heart Transplant
In brief
This study aims to more accurately assess cardiac function, ventilation and exercise capacity in a non-invasive fashion, and to better characterize exercise intolerance in the setting of three populations of individuals with chronic diseases of childhood (acute lymphoblastic leukemia (ALL), chronic lung disease (CLD) of prematurity, and post-heart transplant (HT))
Key facts
- Study ID
- NCT05025774
- Run by
- Masonic Cancer Center, University of Minnesota
- People needed
- 90
- Starts
- 2025-03-14
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2025-11-24
Who can join
Age: 8 and older, up to 25. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Cases:
- Acute lymphoblastic leukemia survivor, OR living with chronic lung disease of prematurity, OR living with heart transplant
- 8-25 years old
- Height: ≥ 48 inches
- Ambulatory without assistance
- English speaking
- Normotensive (<95th percentile for age; okay if managed with antihypertensive medication)
- SpO2 >92%
- Not pregnant
- ALL survivor specific: must have completed therapy ≥ 3 months prior to study entry
- Controls
- 8-25 years old
- Height: ≥ 48 inches
- Ambulatory without assistance
- English speaking
- No history of arrhythmia or known cardiac dysfunction at baseline
- Normotensive (<95th percentile for age; okay if managed with antihypertensive medication)
- SpO2 >95%
- Not pregnant
You may not qualify if…
- Cases:
- ALL specific: received cranial radiation, bone marrow transplant recipients
- Investigator or patient's primary physician deems the patient unsuitable for the study
- Controls:
- History of malignancy, CLD or HT or any other diagnosis which may reduce cardiorespiratory function
- Investigator deems the patient unsuitable for the study
Where it is running
- Masonic Cancer Center — Minneapolis, Minnesota, United States (enrolling)
Full record on ClinicalTrials.gov
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