Haploidentical Hematopoietic Stem Cell Transplantation With Ex Vivo TCR Alpha/Beta and CD19 Depletion in Pediatric Hematologic Malignancies

Recruiting now · Phase 1

Conditions studied: Pediatric Hematologic Malignancies

In brief

This single arm pilot phase I study with safety run-in is designed to estimate the safety and efficacy of a familial mismatched or haploidentical hematopoietic stem cell transplantation (haplo-HSCT) using a novel graft modification technique (selective αβ-TCR and CD19 depletion).

Key facts

Study ID
NCT05011422
Run by
Washington University School of Medicine
People needed
50
Starts
2022-11-03
Expected to finish
2029-05-31
Last updated by the study team
2026-03-16

Who can join

Age: any, up to 30. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.