Laser Photocoagulation of Communicating Vessels in Twin-to-Twin Transfusion Syndrome

Recruiting now

Conditions studied: Twin to Twin Transfusion as Antepartum Condition, Monochorionic Diamniotic Placenta

In brief

The purpose of this study is to evaluate the use of diode laser photocoagulation of the communicating vessels in twin-to- twin transfusion syndrome (TTTS) with respect to maternal, fetal and neonatal outcomes.

Key facts

Study ID

NCT05008744

Run by

Seattle Children's Hospital

People needed

2000

Starts

2021-10-01

Expected to finish

2031-10-01

Last updated by the study team

2024-04-19

Who can join

Age: any. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Single placenta (Monochorionic)
• Polyhydramnios present in recipient twin (Greater than 8 cm maximum vertical pocket below 20 weeks and greater than a 10 cm pocket for greater than 20 weeks gestational age)
• Oligohydramnios present in donor twin (Less than 2 cm maximum vertical pocket)
• Prominent bladder in the recipient/ non-filling bladder in the donor
• Thin dividing membrane

You may not qualify if…

• Patients unwilling to participate in the study or to be followed up
• Presence of major congenital anomalies incompatible with survival
• Active pre-term labor Ruptured membranes
• Chorioamnionitis
• Vaginal bleeding

Where it is running

• Seattle Childrens Hospital — Seattle, Washington, United States (enrolling)
• University of Washington — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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