Regenerative Peripheral Nerve Interfaces to Treat Painful Digit and Hand Neuromas After Amputation

Recruiting now

Conditions studied: Neuroma

In brief

This study is being done to demonstrate the effectiveness of Regenerative Peripheral Nerve Interfaces (RPNI) surgery in treating symptomatic neuromas of the hand and digits following amputation compared to standard of care using a Prospective, Observational Trial

Key facts

Study ID

NCT05008185

Run by

Medstar Health Research Institute

People needed

80

Starts

2021-10-05

Expected to finish

2025-08-01

Last updated by the study team

2024-11-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 18 years or older
• History of unilateral digit, multiple digit, or partial hand amputation
• Discrete neuroma pain on clinical exam
• Following standard of care (SOC), confirmation through a local block and/or ultrasound imaging will be performed if indicated
• Must be seen by a hand therapist for at least 6-week trial of desensitization therapy

You may not qualify if…

• Patients with previous surgical treatment for symptomatic neuromas of the digits or hand
• Patients with other major injuries more proximal in the ipsilateral extremity that cause chronic pain or functional loss
• women pregnant at time of enrollment
• prisoners
• adults who are unable to consent

Where it is running

• The Curtis National Hand Center at Medstar Union Memorial Hospital — Baltimore, Maryland, United States (enrolling)
• University of Michigan Plastic Surgery — Ann Arbor, Michigan, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.