Are Superficial Parasternal Intercostal Plane (SPIP) Blocks With Bupivacaine and With or Without Adjuvants Helpful for Post-operative Pain After Coronary Artery Bypass Grafting?

Status unconfirmed · Not applicable

Conditions studied: Post-operative Pain Management

In brief

The purpose of this study is to determine whether the addition of the superficial parasternal intercostal plane (SPIP) block alone (30cc of 0.25% bupivacaine) or plus Magnesium (200mg of magnesium sulfate) or plus Magnesium + Buprenorphine (300mcg) as adjuvants can improve post-operative pain in patients undergoing cardiothoracic surgery, specifically, coronary artery bypass grafting (CABG)

Key facts

Study ID

NCT05003765

Run by

Wayne State University

People needed

200

Starts

2020-08-06

Expected to finish

2022-05-01

Last updated by the study team

2021-08-12

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients undergoing primary coronary artery bypass grafting

You may not qualify if…

• Patients with significant genetic or acquired clotting/bleeding disorders (hemophilia, DIC, etc.)
• Patients with significant platelet dysfunction
• Infection at site for regional anesthesia
• Allergy to local anesthetics
• Severe aortic stenosis
• Severe mitral stenosis
• Sepsis

Where it is running

• St. Joseph Mercy Oakland Hospital — Pontiac, Michigan, United States (enrolling)

Full record on ClinicalTrials.gov

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