Autologous Mitochondrial Transplant for Cerebral Ischemia

Recruiting now · Not applicable

Conditions studied: Cerebral Ischemia

In brief

The investigators propose to infuse healthy autologous mitochondria into cerebral vessels supplying brain tissue experiencing ischemia in patients who undergo standard-of- care endovascular reperfusion therapy.

Key facts

Study ID

NCT04998357

Run by

University of Washington

People needed

20

Starts

2021-04-29

Expected to finish

2026-10-29

Last updated by the study team

2025-05-21

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Eligible for endovascular thrombectomy to treat acute large vessel occlusion
• Eligible for angioplasty (microcatheter-based balloon/mechanical and chemical angioplasty) to treat acute cerebral vasospasm after aneurysmal subarachnoid hemorrhage
• Subjects for whom there is likely to be enough time to obtain meaningful consent from patient or legally-authorized representative

You may not qualify if…

• Unable to receive a brain MRI scan
• Known mitochondrial disease
• Hemodynamically unstable patients in whom standard of care endovascular reperfusion treatment cannot safely be performed or completed

Where it is running

• Harborview Medical Center — Seattle, Washington, United States (enrolling)

Full record on ClinicalTrials.gov

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