Effects of Pregnancy-Specific Anxiety on Placental Inflammatory and Oxidative Stress Response and Birth Outcomes

Running, not enrolling · Not applicable

Conditions studied: Placental Dysfunction, Prenatal Stress

In brief

Explore the associations of prenatal maternal anxiety to placental histologic findings, and the pro-inflammatory, anti-inflammatory, and immunoregulatory cells found in the placenta and determine the effect of maternal anxiety on the association between placental molecular changes on pregnancy and birth and infant outcomes.

Key facts

Study ID

NCT04993742

Run by

Henry M. Jackson Foundation for the Advancement of Military Medicine

People needed

150

Starts

2019-11-26

Expected to finish

2026-12-31

Last updated by the study team

2026-02-12

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• All Active Duty and DoD beneficiary gravid women,
• 18 years of age or older,
• Receiving prenatal care at BAMC,
• English speaking

You may not qualify if…

• Military dependent daughters
• VA beneficiaries

Where it is running

• Joint Base San Antonio — San Antonio, Texas, United States

Full record on ClinicalTrials.gov

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