A Study of [¹⁴C]-LY3484356 in Healthy Female Participants

Completed · Phase 1

Conditions studied: Healthy

In brief

The main purpose of this study is to measure how much of the study drug gets into the bloodstream and how long it takes the body to get rid of it. This study has two parts. It will involve a single dose of 14C radiolabeled LY3484356. This means that a radioactive substance C14 will be incorporated into the study drug, to investigate the study drug and its breakdown products, to find out how much of these pass from blood into urine, feces and expired air. The study will last about 4 weeks. Screening is required within 28 days prior to the start of the study and follow up is required approximately 7 days after discharge.

Key facts

Study ID

NCT04991766

Run by

Eli Lilly and Company

People needed

16

Starts

2021-08-13

Expected to finish

2022-04-02

Last updated by the study team

2025-12-05

Who can join

Age: 18 and older, up to 65. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Female participants of nonchildbearing potential. This includes females who are not pregnant, non-lactating and either: Infertile due to surgical sterilization or alternate medical cause/congenital or postmenopausal.
• Body mass index (BMI) within the range of 18.0 to 35.0 kilograms per meter squared (kg/m²)

You may not qualify if…

• Significant history or clinical manifestation of any metabolic, allergic, dermatological, hepatic, renal, hematological, pulmonary, cardiovascular, gastrointestinal, neurological, respiratory, endocrine, or psychiatric disorders
• Have evidence of human immunodeficiency virus (HIV) infection and/or positive human HIV antibodies
• Have known allergies to LY3484356, related compounds or any components of the formulation as appropriate, or history of significant atopy

Where it is running

• LabCorp CRU, Inc. — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.