High-definition Surface Electromyography Markers for the Diagnosis of Sarcopenia
Recruiting now · Not applicable
Conditions studied: Sarcopenia
In brief
Sarcopenia is a progressive and generalised skeletal muscle disorder involving the accelerated loss of muscle mass and function that is associated with increased adverse outcomes including falls, functional decline, frailty, and mortality. In this pilot project, the investigators want to explore the potential of the high-definition surface electromyography technology (HD-sEMG) for the diagnosis of sarcopenia. This is a monocentric, descriptive, cross-sectional, parallel group study to develop a new diagnostic method. It is planned to include 50 people aged 75 years and over hospitalized in the acute geriatric ward and suspected of sarcopenia (Score ≥4 on the SARC-F screening questionnaire). The inclusion duration will be 36 months and adding a 1-month patient follow-up as part of routine care, the total study duration will be 37 months. Patients will have their body composition (muscle mass, fat mass, and bone mass) using dual X-ray absorptiometry (DEXA). Muscular strength will be assessed by handgrip strength. Physical performance will be assessed. Additional data will be collected from their medical records.
Key facts
- Study ID
- NCT04987814
- Run by
- Assistance Publique - Hôpitaux de Paris
- People needed
- 175
- Starts
- 2022-05-18
- Expected to finish
- 2026-12-18
- Last updated by the study team
- 2025-05-23
Who can join
Age: 75 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Patient aged 75 years and over
- Score ≥4 on the SARC-F screening questionnaire
- Enrolled in a social security plan (no AME)
- Informed and consenting patient
You may not qualify if…
- BMI ≥30 kg/m2
- Untreated/unbalanced endocrinological pathology
- Myopathy
- Inflammatory or autoimmune pathology
- Severe psychiatric pathology or severe cognitive disorders that do not allow the performance of examinations
- Patients who are dependent for all acts of daily life
- Patients with a very short life expectancy
- Recent fracture or trauma of the lower limbs preventing dynamic measurement of HD-sEMG recording
- Bilateral hip prosthesis
- Skin problem that may interfere with the recording of surface EMG activity
- Patient under guardianship / curatorship
Where it is running
- Service de gériatrie aigue polyvalente (GAP) — Ivry-sur-Seine, France (enrolling)
- Service de soins de suite et de réadaptation Gériatrique 1 — Ivry-sur-Seine, France (enrolling)
- Service de soins de suite et de réadaptation gériatrique 2 — Ivry-sur-Seine, France (enrolling)
- Service de soins de suite et de réadaptation -Plaies et cicatrisation — Paris, France (enrolling)
- Service de soins de suite et de réadaptation Gériatrique Hôpital Rothschild — Paris, France (enrolling)
- Unité d'Explorations fonctionnelles du sujet âgé, Hôpital Charles Foix — Ivry-sur-Seine, France
Full record on ClinicalTrials.gov
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