A Randomized Trial of a Mobile Health Exercise Intervention for Older Adults With Myeloid Neoplasms
Recruiting now · Not applicable · Has a placebo group
Conditions studied: Cancer, Myeloid Neoplasm
In brief
This is a phase 2 randomized controlled trial (RCT) to assess the preliminary efficacy of the a mobile health exercise intervention (GO-EXCAP) versus a chemotherapy education control in 100 older patients with MN receiving outpatient chemotherapy on physical function and patient-reported outcomes (fatigue, mood, and quality of life). We will also explore the effect of the intervention on TNFα and related cytokine gene promoter methylation and their gene and protein expression.
Key facts
- Study ID
- NCT04981821
- Run by
- University of Rochester
- People needed
- 170
- Starts
- 2022-01-03
- Expected to finish
- 2027-12-31
- Last updated by the study team
- 2026-07-15
Who can join
Age: 60 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥60 years (conventional definition of older age in clinical trials of MN)
- Have a diagnosis of MN
- Planned for or receiving outpatient cancer-directed treatments (participants receiving consolidative or maintenance outpatient therapies after induction chemotherapy are allowed to enroll)
- English speaking
- Eastern Cooperative Oncology Group (ECOG) performance status of 0-3
- No medical contraindications for exercise per oncologist
- Able to walk 4 meters as part of Short Physical Performance Battery measured walk (with or without assistive device)
- Able to provide informed consent
You may not qualify if…
- Physical, psychological, or social impairments that would interfere with subject's ability to participate in the study or participate in the intervention, as determined by the PI or the treating team
Where it is running
- University of Rochester Medical Center/Wilmot Cancer Institute — Rochester, New York, United States (enrolling)
Full record on ClinicalTrials.gov
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