Using a Telemedicine Approach in a Genome-wide Association Study of Atopic Dermatitis - Searching for Novel Biomarkers in Clinically Relevant Phenotypes

Withdrawn before enrolling

Conditions studied: Atopic Dermatitis, Eczema, DNA

In brief

Atopic eczema is a common skin disorder affecting at least 2-3% of the western population. Atopic eczema cannot be cured and therefore treatment aims to alleviate the symptoms of the disease. Today, many different medical treatments are available: from mild hormone creams to harsh systemic treatments. The treatment chosen depends in part on the severity of the eczema and on the treatment response of the individual. This practice may mean that some people with eczema undergo unnecessary treatment courses with associated side effects. We know today that eczema has a hereditary component, and different areas have been identified in the hereditary material that appear to play a role. Although it is thought that variations in specific areas of the inheritance material may influence how eczema is expressed in the individual, the significance of these variations is far from clarified. The investigators want to increase the knowledge about atopic eczema, about the disease and how in the future we can organize the treatment of eczema based on knowledge of our genetic material. In this study, the investigators want to elucidate whether there is a correlation between specific variations in the genetic material and how the eczema is clinically expressed. In addition, the investigators want to assess whether reports with specific information about the individual's genetic material in relation to his or her lifestyle can help retain participants in research projects.

Key facts

Study ID

NCT04965233

Run by

Studies&Me

People needed

0

Starts

2020-11-30

Expected to finish

2021-12-31

Last updated by the study team

2021-09-20

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Informed consent has been signed
• 18 years or older
• Resident in the USA or Denmark
• AD meeting the UK Diagnostic Criteria for Atopic Dermatitis
• At least one visible AD lesion at the time of recruitment (as confirmed remotely through photo upload in screening)
• Smartphone user with daily access to internet (WIFI or 3G/4G)
• Willing to donate a DNA sample
• Confirmed intention to comply with study protocol procedures

You may not qualify if…

• Female subjects that are pregnant (or plan to become so during the study period) or lactating
• Active dermatological condition that may confound the diagnosis of AD and/or the assessment of disease activity
• Unable to speak or understand English or Danish
• Overlap with participation in interventional trials
• No visible AD at time of screening
• Any other reasons that in the investigator's opinion could:
• Impede a subject's ability to complete the study period
• Influence the objectivity or quality of the findings of the study

Where it is running

• 450 Broadway F4 — Redwood City, California, United States
• Studies&Me — Copenhagen, Denmark

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.