Study Assessing Long-teRm Outcomes of dupiluMAb (DUPIXENT®) Treatment in Adult Patients With Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)
Running, not enrolling
Conditions studied: Chronic Rhinosinusitis With Nasal Polyposis
In brief
The primary objectives of the study are: * To longitudinally characterize the long-term effectiveness of DUPIXENT® through assessment of patient-reported symptoms, Health-Related Quality of Life (HRQoL) related to Chronic rhinosinusitis with nasal polyposis (CRSwNP) and other type 2 comorbidities, and their change over-time. * To characterize patients who receive DUPIXENT® for CRSwNP in a real-world setting with respect to their medical history, demographic and disease characteristics, and type 2 comorbidities The secondary objectives of the study are: * To characterize real-world utilization of DUPIXENT® for patients with CRSwNP * To collect patient and physician global assessment of disease severity and treatment satisfaction for patients receiving DUPIXENT® for CRSwNP * To collect long-term safety data for patients receiving DUPIXENT® for CRSwNP
Key facts
- Study ID
- NCT04959448
- Run by
- Regeneron Pharmaceuticals
- People needed
- 717
- Starts
- 2021-08-12
- Expected to finish
- 2027-03-25
- Last updated by the study team
- 2026-07-13
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Medical Research of Arizona, a division of Allergy, Asthma & Immunology Associates — Scottsdale, Arizona, United States
- The Allergy and Rheumatology Medical Clinic — La Jolla, California, United States
- ARK Clinical Research — Long Beach, California, United States
- Scripps Health - Scripps Clinic Carmel Valley — San Diego, California, United States
- Breathe Clear Institute — Torrance, California, United States
- Allergy & Asthma Clinical Research — Walnut Creek, California, United States
- AADRS Clincial Research Center — Coral Gables, Florida, United States
- University of Florida — Gainesville, Florida, United States
- Damask Physicians Group — Lake Mary, Florida, United States
- University of South Florida — Tampa, Florida, United States
- Emory University Hospital Midtown — Atlanta, Georgia, United States
- IACT Health — Columbus, Georgia, United States
- Treasure Valley Medical Research — Boise, Idaho, United States
- Northwestern University Feinberg School of Medicine — Chicago, Illinois, United States
- University of Illinois — Chicago, Illinois, United States
- The University of Chicago Medical Center UCMC Duchossois Center for Advanced Medicine DCAM — Chicago, Illinois, United States
- Asthma & Allergy Center of Chicago — Oak Park, Illinois, United States
- Indiana University Health — Indianapolis, Indiana, United States
- John Hopkins University School Of Medicine — Baltimore, Maryland, United States
- Brigham & Women's Hospital — Boston, Massachusetts, United States
- University of Michigan, Michigan Medicine Pulmonary Clinic — Ann Arbor, Michigan, United States
- Allergy & Asthma Center of Minnesota - Allergology — Maplewood, Minnesota, United States
- University of Missouri — Columbia, Missouri, United States
- University of Nebraska Medical Center — Omaha, Nebraska, United States
- Excel ENT of Alabama — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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