Retinoblastoma Patient Clinical Database and Tissue Repository

Recruiting now

Conditions studied: Retinoblastoma, Retinoblastoma Bilateral, Retinoblastoma Unilateral

In brief

Retinoblastoma (RB) is a primary eye cancer that forms in the back of the eye of infants and toddlers. Traditionally, RB is diagnosed without a biopsy; tumor can only be studied once an eye has been surgically removed. Given this limitation, we use aqueous humor (AH), the clear fluid in the front of the eye to detect specific markers, or information, that comes from the tumor itself.

Key facts

Study ID

NCT04959097

Run by

Children's Hospital Los Angeles

People needed

800

Starts

2017-01-01

Expected to finish

2030-12-31

Last updated by the study team

2026-04-22

Who can join

Age: any, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All patients, age 0 days to 18 years, with a diagnosis unilateral or bilateral retinoblastoma (RB) seen at CHLA (Children's Hospital Los Angeles).

You may not qualify if…

• Patients referred for second opinions only and not treated at CHLA for any reason.

Where it is running

• Phoenix Children's Hospital — Phoenix, Arizona, United States (enrolling)
• Children's Hospital Los Angeles — Los Angeles, California, United States (enrolling)
• Emory University Children's Healthcare of ATL — Atlanta, Georgia, United States (enrolling)
• Ann & Robert H. Lurie Children's Hospital of Chicago — Chicago, Illinois, United States (enrolling)
• Oregon Health & Science University: Casey Eye Institute — Portland, Oregon, United States (enrolling)
• Wills Eye Institute — Philadelphia, Pennsylvania, United States (enrolling)
• St. Jude Children's Research Hospital — Memphis, Tennessee, United States (enrolling)
• Seattle Children's Hospital; University of Washington — Seattle, Washington, United States (enrolling)
• The Hospital for Sick Children (Toronto SickKids) — Toronto, Ontario, Canada (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.