Melatonin and Vaccine Response, Immunity, and Chronobiology Study

Status unconfirmed · Not applicable

Conditions studied: Vaccine Response, Sleep, Circadian Rhythm Disorders

In brief

This study will evaluate the impact of sleep, circadian health and melatonin on flu vaccine immunogenicity.

Key facts

Study ID

NCT04953754

Run by

Walter Reed National Military Medical Center

People needed

200

Starts

2022-10-25

Expected to finish

2025-06-01

Last updated by the study team

2023-10-10

Who can join

Age: 18 and older, up to 64. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 18-64
• Eligible to receive flu vaccination (at military hospital, DEERS eligible)

You may not qualify if…

• Allergy or contraindication to getting flu vaccine
• Pregnancy or likelihood of getting pregnant in next few weeks
• Medical history of doctor diagnosed immune-compromising condition (HIV/AIDS, cancer, diabetes, significant cardiovascular disease) or doctor diagnosed sleep disorder (insomnia, narcolepsy).*Sleep apnea is an exclusion unless stable on treatment with cpap or oral device for more than3 months.
• Currently taking any immune suppressants or immunomodulating treatments (systemic corticosteroids, chemotherapy, etc, within the past 3 months) or sleep medication or supplement (including over the counter medications and melatonin, within the past 1 month).

Where it is running

• Naval Support Activity — Bethesda, Maryland, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.