Pulmonary Vascular Hemodynamics Before and After Mitral Valve Procedures

Withdrawn before enrolling

Conditions studied: Pulmonary Hypertension

In brief

The objective of this proposal is to study circulating and echocardiographic markers of pulmonary vascular and right ventricular remodeling in patients with a WHO-2 diagnosis of pulmonary hypertension after mitral valve procedures. The investigators are proposing the study will be impactful for the early detection and prediction and of residual pulmonary hypertension (PH) that would otherwise be undetected and fatal with no curative treatment.

Key facts

Study ID

NCT04947384

Run by

University of Alabama at Birmingham

People needed

0

Starts

2021-12-21

Expected to finish

2026-01-20

Last updated by the study team

2026-01-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• >= 18 years/old

You may not qualify if…

• Patients with ejection fraction (EF) < 35%
• Patients with severe tricuspid valve regurgitation
• Transplant patients
• Patients scheduled for ventricular assist devices
• Patients with a diagnosis of heart failure with preserved ejection fraction
• Any aortic valvular disease

Where it is running

• The University of Alabama at Birmingham — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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