Aligning Medications With What Matters Most
Completed · Not applicable
Conditions studied: Polypharmacy, Alzheimer Disease and Related Dementias
In brief
The Aligning Medications with What Matters Most (ALIGN) study will assess the feasibility and preliminary efficacy of a deprescribing intervention to reduce medication regimen complexity and treatment burden for people living with dementia (PLWD) and their care partners.
Key facts
- Study ID
- NCT04938648
- Run by
- Johns Hopkins University
- People needed
- 138
- Starts
- 2021-06-03
- Expected to finish
- 2022-05-02
- Last updated by the study team
- 2026-06-17
Who can join
Age: 65 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age 65 or greater
- Diagnosis of dementia from International Classification of Diseases (ICD) -9 or ICD-10 codes
- At least one other chronic condition
- Five or more chronic medications (to include all prescription and over-the-counter medications, both scheduled and as needed)
- Have a primary care physician at the pilot clinic who has enrolled in the study; this will be defined as having had at least 1 previous visit with that physician
- Care partners:
- Family or other companions age 21 years or greater who regularly help the patient with managing medications
You may not qualify if…
- As both the pilot and the planned pragmatic trial will be based in primary care, individuals residing in long term care facilities or enrolled in hospice will be excluded.
- Individuals who cannot converse comfortably in English will be excluded because the FCMAHS has not been validated in other languages.
Where it is running
- Kaiser Permanente — Aurora, Colorado, United States
- Johns Hopkins Bayview Medical Center — Baltimore, Maryland, United States
Full record on ClinicalTrials.gov
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