Early Caries Lesion Management Observational Study
Status unconfirmed
Conditions studied: Initial Caries, Arrested Dental Caries, Cavitated Caries, Dental Caries, Dental Caries in Children
In brief
The purpose of this observational study is to assess the effectiveness of Curodont Repair Fluoride Plus (CRFP) compared to other tooth-specific treatments (silver diamine fluoride (SDF), sealants, or other FDA-approved treatments) in preventing progression to cavitation in patients with at least one early non-cavitated dental caries lesion. The study will also evaluate the effectiveness of CRFP in comparison to no tooth-specific treatment control groups, including whole mouth treatments such as: 2.26% fluoride varnish, 1.23% fluoride foam, and 5000 ppm fluoride prescription toothpaste; and no treatment, on caries arrest and in preventing progression to cavitation in patients with at least one early non-cavitated dental lesion.
Key facts
- Study ID
- NCT04933331
- Run by
- CareQuest Institute for Oral Health
- People needed
- 744
- Starts
- 2020-12-07
- Expected to finish
- 2024-03-31
- Last updated by the study team
- 2023-11-24
Who can join
Age: 4 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- All patients with permanent teeth who are diagnosed with at least one American Dental Association Caries Classification System (ADACCS) "Initial" caries lesion in a permanent tooth, will be included in this analysis.
You may not qualify if…
- Primary teeth
- Permanent teeth with ADACCS "Moderate" or "Advanced" caries lesions
- Healthy/ ADACCS "Sound" teeth
Where it is running
- Sarrell Dental Clinic — Dothan, Alabama, United States
- DentaQuest (Advantage Dental) Oral Health Center — Westborough, Massachusetts, United States
- Advantage Dental Oral Health Center — Bend, Oregon, United States
- Community Dental Care — Dallas, Texas, United States
Full record on ClinicalTrials.gov
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