DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Recruiting now · Phase 2
Conditions studied: Relapsed Diffuse Large B-cell Lymphoma, Refractory Diffuse Large B-cell Lymphoma
In brief
This is a Phase 2b, randomized, open label study to assess the safety and efficacy of DPX-Survivac and pembrolizumab, with and without low-dose cyclophosphamide (CPA) in subjects with relapsed or refractory DLBCL.
Key facts
- Study ID
- NCT04920617
- Run by
- ImmunoVaccine Technologies, Inc. (IMV Inc.)
- People needed
- 102
- Starts
- 2021-06-18
- Expected to finish
- 2025-04-01
- Last updated by the study team
- 2023-04-07
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Hospital Universitario Virgen del Rocío — Seville, Spain (enrolling)
- University Clinical Center of Serbia — Belgrade, Serbia (enrolling)
- Oncology Institute of Vojvodina — Kamenitz, Serbia (enrolling)
- University Clinical Center Kragujevac — Kragujevac, Serbia (enrolling)
- Clinical Hospital Center Zemun — Zemun, Serbia (enrolling)
- Hospital Santa Creu i Sant Pau — Barcelona, Spain (enrolling)
- Hospital Universitario de Burgos — Burgos, Spain (enrolling)
- Compassionate Cancer Care Medical Group — Fountain Valley, California, United States (enrolling)
- Blood and Marrow Transplant Group of Georgia — Atlanta, Georgia, United States (enrolling)
- Indiana University Health Melvin and Bren Simon Cancer Center — Indianapolis, Indiana, United States (enrolling)
- Tulane Cancer Center Office of Clinical Research — New Orleans, Louisiana, United States (enrolling)
- Oncology Hematology West, PC dba Nebraska Cancer Specialists — Omaha, Nebraska, United States (enrolling)
- Christus St. Vincent Regional Cancer Center — Santa Fe, New Mexico, United States (enrolling)
- Brody School of Medicine at East Carolina University — Greenville, North Carolina, United States (enrolling)
- Toledo Clinic Cancer Center — Toledo, Ohio, United States (enrolling)
- Allegheny Health Network (AHN) West Penn Hospital — Pittsburgh, Pennsylvania, United States (enrolling)
- Reading Hospital - McGlinn Cancer Institute — West Reading, Pennsylvania, United States (enrolling)
- Royal Adelaide Hospital — Adelaide, South Australia, Australia (enrolling)
- Epworth Freemasons Hospital — Melbourne, Victoria, Australia (enrolling)
- Box Hill Hospital — Melbourne, Victoria, Australia (enrolling)
- Westmead Hospital — Westmead, Australia (enrolling)
- Saskatoon Cancer Center — Saskatoon, Saskatchewan, Canada (enrolling)
- Hôpital Avicenne — Bobigny, France (enrolling)
- Centre d'Oncologie de Gentilly — Nancy, France (enrolling)
- Hôpital Privé du Confluent — Nantes, France (enrolling)
Full record on ClinicalTrials.gov
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