Functional Digestive Disorders Observatory
Recruiting now
Conditions studied: Irritable Bowel Syndrome, Dyspepsia, Functional Constipation, Faecal Incontinence, Abdominal Pain (AP), Vomiting Syndrome
In brief
Functional digestive pathologies are defined by symptoms such as functional dyspepsia, gastroesophageal reflux, irritable bowel syndrome, gastroesophageal reflux, functional constipation, functional diarrhea, functional bloating, the opioid-induced constipation and fecal incontinence, without organic substratum. These diseases are very common in the general population (20%) and represent the first cause of consultation in city gastroenterology. The pathophysiology of these functional disorders is complex and often multifactorial: disturbances in digestive motility, altered visceral sensitivity, sphincter dysfunction, post-surgery, intestinal inflammation, dysbiosis, and impairment of the gut-brain axis. For example, it has been shown that one in four patients with inflammatory bowel disease in confirmed remission report digestive symptoms consistent with a functional bowel disorder, suggesting a possible pathophysiological continuum between these two conditions. The objective of this study is to collect prospective clinical and tests data and a biological collection from biological samples (digestive biopsies, blood, urine and fecal samples) collected as part of the standard care. This collection could identify diagnostic or prognostic markers of the therapeutic response.
Key facts
- Study ID
- NCT04918329
- Run by
- University Hospital, Rouen
- People needed
- 2000
- Starts
- 2020-10-09
- Expected to finish
- 2030-10-09
- Last updated by the study team
- 2026-01-08
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients over 18 years of age;
- Patients with functional digestive disorder for more of 3 months;
- Patients assessed as part of routine care;
- Patients affiliated to the Social Security ;
- Patients not opposed to participation in the Centre
You may not qualify if…
- Person deprived of liberty by administrative or judicial decision or major protected subject (under guardianship or curatorship);
- Patients unable for any reason to read, understand, respond questionnaires (visual, psychiatric, cognitive, etc.)
Where it is running
- Physiology Unit, Hopital Charles Nicolle, 1 rue de Germont — Rouen, France (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.