Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol
Completed · Not applicable
Conditions studied: Anxiety Disorders, Depression, Posttraumatic Stress Disorder
In brief
The proposed project aims to test the cognitive and neural effects of a cognitive training in a sample of individuals seeking treatment for anxiety, depression, or traumatic stress symptoms. Participants will be randomly assigned to a high dose, low dose, or assessment only condition. Participants will be compared on cognitive performance and brain response during cognitive tasks from baseline to post-treatment.
Key facts
- Study ID
- NCT04912089
- Run by
- University of California, San Diego
- People needed
- 73
- Starts
- 2021-10-15
- Expected to finish
- 2023-06-30
- Last updated by the study team
- 2025-07-23
Who can join
Age: 21 and older, up to 55. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- age 21-55
- fluent in English
- diagnosis of mood, anxiety, or traumatic stress disorder
- clinically elevated repetitive negative thinking
- outpatient status
- 6-week stability if taking selective serotonin reuptake inhibitor (SSRI) medications
You may not qualify if…
- past year diagnosis of severe alcohol or moderate or greater substance use disorder
- lifetime history of psychotic or bipolar I disorder
- acute suicidality necessitating immediate clinical intervention
- neurodegenerative or neurodevelopmental disorders
- history of moderate or severe traumatic brain injury or other known neurological condition
- sensory deficits that would preclude completing tasks
- conditions unsafe for completing MRI scanning (e.g., metal in body)
- currently receiving psychosocial treatment
- currently receiving psychiatric pharmacotherapy, except SSRIs
Where it is running
- UC San Diego — San Diego, California, United States
Full record on ClinicalTrials.gov
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