Long-term Follow-up Study of Allogeneic Gamma Delta (γδ) CAR T Cells
Running, not enrolling
Conditions studied: Lymphoma, Follicular, Lymphoma, Mantle-Cell, Marginal Zone Lymphoma, Primary Mediastinal B-cell Lymphoma, Diffuse Large B Cell Lymphoma, Lymphoma, Non-Hodgkin
In brief
The purpose of this study is to assess long-term side effects from subjects who receive an Adicet Bio γδ CAR T cell product. Subjects will join this study once they complete the parent interventional study. No additional study drug will be given, but subjects can receive other therapies for their cancer while they are being followed for long term safety in this study. For a period of 15 years from the first administration of Adicet Bio allogeneic γδ CAR T cell product, subjects will be assessed for long-term safety and survival through collection of data that include safety, efficacy, pharmacokinetics and immunogenicity.
Key facts
- Study ID
- NCT04911478
- Run by
- Adicet Therapeutics
- People needed
- 50
- Starts
- 2022-02-14
- Expected to finish
- 2039-08-01
- Last updated by the study team
- 2026-04-09
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- All patients who received any Adicet allogeneic CAR T investigational product and have either completed the core treatment protocol or have discontinued early
- All patients who are willing and able to adhere to the study visit schedule and other protocol requirements.
- Capable of giving signed informed consent which includes compliance with requirements and restrictions listed in the informed consent form (ICF) and protocol
You may not qualify if…
- There are no specific exclusion criteria for this study
Where it is running
- Blood and Marrow Transplant Program — Palo Alto, California, United States
- Norton Cancer Institute — Louisville, Kentucky, United States
- Baylor Scott & White Research Institute — Dallas, Texas, United States
- MD Anderson Caner Center — Houston, Texas, United States
- Medical College of Wisconsin — Milwaukee, Wisconsin, United States
Full record on ClinicalTrials.gov
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