Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients With Brain Tumors
Recruiting now · Not applicable
Conditions studied: Malignant Brain Glioma
In brief
This trial studies how well spectroscopic magnetic resonance imaging (MRI) guided proton therapy works in assessing metabolic change in pediatric patients with brain tumors. The non-invasive imaging, such as spectroscopic MRI may help to map the differences in tumor metabolism compared to healthy tissue without injection of any contrast agent.
Key facts
- Study ID
- NCT04908709
- Run by
- Emory University
- People needed
- 25
- Starts
- 2018-12-20
- Expected to finish
- 2030-10-13
- Last updated by the study team
- 2026-03-04
Who can join
Age: any, up to 21. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Pathologically diagnosed high-grade glioma (World Health Organization [WHO] grade 3-4). Patients with a radiographically diagnosed high-grade glioma may enroll prior to pathologic confirmation, but would be removed from study if pathology did not confirm the diagnosis of high-grade glioma.
- Primary tumor located within the supratentorial brain.
- Recommended to receive definitive radiation therapy.
- Able to receive MRI scans.
- Both males and females, and members of all races and ethnic groups are eligible for this trial.
You may not qualify if…
- Patients with pacemakers, non-titanium aneurysm clips, neurostimulators, cochlear implants, non-titanium metal in ocular structures, or other incompatible implants which makes MRI safety an issue are excluded.
- Patients that have any significant medical illnesses that in the investigator's opinion cannot be adequately tolerate MRI scan are excluded.
- Pathology demonstrated low-grade glioma or other benign or non-invasive brain tumor.
Where it is running
- Emory Proton Therapy Center — Atlanta, Georgia, United States (enrolling)
- Emory University Hospital/Winship Cancer Institute — Atlanta, Georgia, United States (enrolling)
- Children's Healthcare of Atlanta - Scottish Rite — Atlanta, Georgia, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.