Excimer Laser Trabeculostomy Glaucoma Treatment Study

Completed · Not applicable

Conditions studied: Glaucoma, Primary Open Angle

In brief

Evaluation of the safety and effectiveness of the ELIOS System procedure to reduce intraocular pressure (IOP) in adult subjects with mild to moderate primary open-angle glaucoma (POAG) undergoing cataract surgery

Key facts

Study ID

NCT04899063

Run by

Elios Vision, Inc.

People needed

318

Starts

2021-05-10

Expected to finish

2025-07-29

Last updated by the study team

2026-06-16

Who can join

Age: 45 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of mild to moderate POAG
• Operable cataract, eligible for phacoemulsification with a BCVA of 20/40 or worse
• Medicated IOP of <=24 mmHg
• Unmedicated diurnal IOP of >=22 mmHg and <=34 mmHg
• Shaffer angle grade of III or IV
• CD ratio <=0.8
• At least 45 years old

You may not qualify if…

• Closed-angle and secondary glaucomas
• Prior incisional glaucoma surgery, intraocular surgery, or corneal surgery
• Cannot undergo medication washout in the study eye
• Diagnosis of degenerative visual disorders
• Non-study eye with BCVA worse than 20/80
• Known corticosteroid responder
• Pregnant or nursing women; or women of childbearing potential not using medically acceptable birth control

Where it is running

• ELIOS Vision Clinical Site — Glendale, Arizona, United States
• ELIOS Vision Clinical Site — Petaluma, California, United States
• ELIOS Vision Clinical Site — Fort Collins, Colorado, United States
• ELIOS Vision Clinical Site — Grand Junction, Colorado, United States
• ELIOS Vision Clinical Site — DeLand, Florida, United States
• ELIOS Vision Clinical Site — Largo, Florida, United States
• ELIOS Vision Clinical Site — Melbourne, Florida, United States
• ELIOS Vision Clinical Site — Vero Beach, Florida, United States
• ELIOS Vision Clinical Site — Rock Island, Illinois, United States
• ELIOS Vision Clinical Site — Overland Park, Kansas, United States
• ELIOS Vision Clinical Site — Chaska, Minnesota, United States
• ELIOS Vision Clinical Site — St Louis, Missouri, United States
• ELIOS Vision Clinical Site — Las Vegas, Nevada, United States
• ELIOS Vision Clinical Site — South Orange, New Jersey, United States
• ELIOS Vision Clinical Site — Oklahoma City, Oklahoma, United States
• ELIOS Vision Clinical Site — Duncanville, Texas, United States
• ELIOS Vision Clinical Site — El Paso, Texas, United States
• Elios Vision Clinical Site 2 — San Antonio, Texas, United States
• ELIOS Vision Clinical Site — San Antonio, Texas, United States
• ELIOS Vision Clinical Site — Kenosha, Wisconsin, United States

Full record on ClinicalTrials.gov

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