Cardiopulmonary Rehabilitation in COVID-19 Longhaulers
Status unconfirmed · Not applicable · Has a placebo group
Conditions studied: Covid19, Viral Syndrome
In brief
This study will test the efficacy of treadmill exercise combined with supplemental oxygen during exercise and recovery for the treatment of persistent post-acute COVID-19 symptoms. Participants will be pseudo-randomized (stratified by age) to one of four conditions for 8 treatment sessions: 1) treadmill exercise plus supplemental oxygen, 2) treadmill exercise plus air, 3) supplemental oxygen only, 4) air only. All participants will then cross-over and receive 16 additional sessions of treadmill exercise plus supplemental oxygen.
Key facts
- Study ID
- NCT04898205
- Run by
- Noah Greenspan
- People needed
- 24
- Starts
- 2021-01-21
- Expected to finish
- 2022-01-20
- Last updated by the study team
- 2021-05-25
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Between the ages of 18-60
- Contracted COVID-19 between February - July 2020
- Has been clinician-diagnosed with COVID-19 based on PCR/antigen testing, antibody testing, or clinical symptoms
- Is currently experiencing one or more of the following symptoms, which began only after contracting COVID-19 : dyspnea, cough, chest pain, tachycardia or other arrhythmias, hypertension, hypotension, blood pressure lability, oxygen desaturation, exercise/activity intolerance, fatigue, or dizziness.
- Has been cleared by a physician for exercise and supplemental oxygen.
- Has the capacity to provide written, informed consent
- Able to complete questionnaires in English
You may not qualify if…
- History of any of the following per the American College of Sports Medicine exercise testing guidelines (American College of Sports Medicine et al., 2018) to be determined during a screening consultation:
- Acute myocardial infarction within the past two days
- Ongoing unstable angina
- Uncontrolled cardiac arrhythmias
- Active endocarditis
- Symptomatic severe aortic stenosis
- Decompensated heart failure
- Active pulmonary embolism, pulmonary infarction, or deep venous thrombosis
- Active myocarditis or pericarditis
- Acute aortic dissection
- Physical disability that precludes safe and adequate testing
- Participants who demonstrate orthostatic intolerance or oxygen desaturation (<90%) during the exercise tolerance test will no longer be eligible for the study because it is not safe for them to exercise on a treadmill.
Where it is running
- Post-COVID Rehabilitation and Recovery Clinic at H&D Physical Therapy — New York, New York, United States (enrolling)
Full record on ClinicalTrials.gov
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