Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Ischemic Stroke, Cognitive Impairment

In brief

The purpose of this study is to determine whether a non-invasive brain stimulation technique, transcranial direct current stimulation (tDCS), combined with traditional cognitive therapy will improve cognitive function in patients with subacute stroke.

Key facts

Study ID

NCT04897334

Run by

University of Pennsylvania

People needed

70

Starts

2021-09-21

Expected to finish

2028-01-01

Last updated by the study team

2026-01-09

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Stroke that occurred within 4 weeks of the study
• Presence of cognitive impairment attributable to stroke
• Between the ages of 18 and 90
• Able to understand the nature of the study and give informed consent
• Able to follow simple commands as evidenced by NIHSS subtest 1C =0

You may not qualify if…

• History of chronic, serious, or unstable neurologic illness other than stroke
• Current unstable medical illness(es)
• History of reoccurring seizures or epilepsy
• Current abuse of alcohol or drugs (prescription or otherwise)
• Active and severe psychiatric disorder
• Metallic objects in the face or head other than dental apparatus such as braces, fillings, and implants.
• Pregnancy

Where it is running

• Penn Medicine Rehabilitation — Philadelphia, Pennsylvania, United States (enrolling)

Full record on ClinicalTrials.gov

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