Study of Sitravatinib With or Without Other Anticancer Therapies Receiving Clinical Benefit From Parent Study

Completed · Phase 2/Phase 3

Conditions studied: Advanced or Metastatic Solid Malignancies

In brief

A Study of Sitravatinib Alone or in Combination with Other Anticancer Therapies in Advanced or Metastatic Malignancies

Key facts

Study ID

NCT04887870

Run by

Mirati Therapeutics Inc.

People needed

49

Starts

2021-06-29

Expected to finish

2025-09-25

Last updated by the study team

2026-08-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Currently receiving sitravatinib single- agent or in combination with other therapeutic agent(s) in another Mirati- sponsored protocol
• Currently tolerating the treatment regimen in the parent protocol
• Experiencing clinical benefit with or without prior radiographic progression from the treatment regimen in the parent protocol in the opinion of the investigator and the investigator determines that continuing treatment is in the patient's best interest

You may not qualify if…

• Known or suspected presence of other cancer
• Other life- threatening illness or organ system dysfunction compromising safety evaluation

Where it is running

• Rocky Mountain Cancer Centers - Littleton — Littleton, Colorado, United States
• Local Institution - 516-014-029 — Goshen, Indiana, United States
• Local Institution - 516-014-002 — Boston, Massachusetts, United States
• Barbara Ann Karmanos Cancer Institute — Detroit, Michigan, United States
• Local Institution - 516-014-005 — Minneapolis, Minnesota, United States
• Urology Cancer Center and GU Research Network — Omaha, Nebraska, United States
• Local Institution - 516-014-011 — Albany, New York, United States
• Memorial Sloan Kettering Cancer Center - Arnold and Marie Schwartz Cancer Research Building — New York, New York, United States
• Local Institution - 516-014-004 — Columbus, Ohio, United States
• Local Institution - 516-014-001 — Austin, Texas, United States
• USOR - Texas Oncology Northeast Texas - Denison — Denison, Texas, United States
• Local Institution - 516-014-013 — Houston, Texas, United States
• NEXT Virginia — Fairfax, Virginia, United States

Full record on ClinicalTrials.gov

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