Dynamics of Markers of Infection and Inflammation in Hospitalized Coronavirus Disease 2019 (COVID-19) Patients

Recruiting now

Conditions studied: COVID-19 Respiratory Infection

In brief

Patients requiring admission to the hospital due to a moderate and severe COVID-19 infection may differ in their ability to respond to viral infection and to eliminate viral load. Several comorbidities and interventions like antivirotic or antiinflammatory treatment may also modify expected patients response and decrease of viral load. In this observational study, evolution of selected inflammatory markers, indicators of severity of infection and patient characteristics will be followed and recorded in hospitalized patients with COVID-19.

Key facts

Study ID

NCT04887623

Run by

University Hospital Hradec Kralove

People needed

30

Starts

2021-04-01

Expected to finish

2026-08-01

Last updated by the study team

2024-05-10

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• SARS CoV2 positive test within last 14 day
• bilateral infiltrates on chest X.ray or CT
• need for oxygen to keep pulse oximetry saturation above 92% or other respiratory support measures (HFNO, non-invasive ventilation or invasive ventilation)

You may not qualify if…

• known history of intersticial lung disease
• known history of congestive heart failure

Where it is running

• University Hospital Hradec Kralove — Hradec Králové, Czechia (enrolling)

Full record on ClinicalTrials.gov

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