Effect of Preoperative Fiber on Postoperative Bowel Function
Completed · Not applicable
Conditions studied: Constipation, Prolapse, Vaginal
In brief
Post-operative constipation is one of the most common complaints after pelvic organ prolapse surgery. Psyillum fiber is an FDA-approved, over the counter dietary supplement that is commonly used to treat constipation. The investigators are conducting this study to determine if participants who receive psyllium fiber before surgery have less difficulty with their first bowel movement after surgery.
Key facts
- Study ID
- NCT04882995
- Run by
- University of Massachusetts, Worcester
- People needed
- 84
- Starts
- 2019-05-13
- Expected to finish
- 2021-06-01
- Last updated by the study team
- 2022-06-28
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- Women undergoing prolapse repair with or without hysterectomy on the University of Massachusetts urogynecology service
You may not qualify if…
- Unable to provide consent
- Under 18 years of age
- Pregnant women
- Prisoners
- As our validated questionnaires are only available in English, we are unable to offer study participation to Non-English speaking subjects
- Because these conditions intrinsically affect bowel function, women with the following will be excluded: history of inflammatory bowel disease, colorectal cancer, rectovaginal fistula, sigmoid resection or rectal surgery
- Because the use of motility agents can affect bowel function and stool transit, women using motility agents such as linaclotide will be excluded.
- Concurrent bowel surgery due to potential effect on the surgical field
- Concurrent anal sphincteroplasty due to potential effect on the surgical field
- Insulin-dependent diabetes mellitus with known gastroparesis as this would affect transit of fiber supplement
- Patients with a history of phenylketonuria as the psyllium fiber supplement we will be using contains phenylalanine
- History of placement of sacral neuromodulating device for indication of fecal incontinence, as this would affect bowel function
Where it is running
- University of Massachusetts Memorial Medical Center — Worcester, Massachusetts, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.