Improving HIV Diagnosis, Linkage to Care, and Prevention Services With HIV Point-of-Care Nucleic Acid Tests

Recruiting now · Not applicable

Conditions studied: HIV Infections

In brief

This project will develop, implement, and evaluate models for use of point-of-care nucleic acid testing (POC NAT) among HIV-negative persons seeking HIV testing, PEP, and PrEP and HIV-positive persons in community and clinical settings. Study aims #1 and #2 will evaluate the sensitivity and specificity of a qualitative POC NAT in persons not known to be HIV-positive and will determine the impact of its use on PrEP uptake and persistence among persons testing HIV-negative and on time to HIV continuum of care outcomes among persons testing HIV-positive. Aim #3 will implement a POC NAT-tailored behavioral intervention to evaluate impact on time to virologic suppression among PLWH receiving ART. Aim #4 will quantify the acceptability and feasibility of implementation of POC NAT in community and clinical settings and collect cost and related data for cost-effectiveness analyses. Finally, in Aim #5, a distinct but related study will compare the sensitivity, specificity, and agreement of multiple POC NATs over a range of HIV RNA levels.

Key facts

Study ID

NCT04880200

Run by

University of Washington

People needed

932

Starts

2022-01-03

Expected to finish

2024-08-31

Last updated by the study team

2023-04-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Persons who are HIV-positive and seeking care at Madison Clinic.
• 18 years of age or older
• Patient's provider is willing to deliver adherence intervention
• Patient is getting a laboratory RNA viral load test that day.
• Able to read and speak English

You may not qualify if…

• Patients of unknown HIV status
• Patients who have participated in the study before

Where it is running

• Madison Clinic — Seattle, Washington, United States (enrolling)

Full record on ClinicalTrials.gov

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