STIMULUS MDS-US : Sabatolimab Added to HMA in Higher Risk MDS

Stopped early · Phase 2

Conditions studied: Myelodysplastic Syndrome (MDS)

In brief

The main objective of this study was to assess the safety profile of MBG453 (sabatolimab) in combination with FDA approved hypomethylating agents (HMAs) of investigator's choice (IV Decitabine or Azacitidine /SC Azacitidine /Oral Decitabine (cedazuridine combination (INQOVI))).

Key facts

Study ID
NCT04878432
Run by
Novartis Pharmaceuticals
People needed
39
Starts
2022-03-17
Expected to finish
2024-09-01
Last updated by the study team
2025-10-16

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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