Neurofeedback Intervention for Reading Deficits in Subacute Stroke
Recruiting now · Not applicable · Has a placebo group
Conditions studied: Stroke, Dyslexia, Acquired
In brief
The overall goal of this project is to advance a biologically-based approach to treatment of reading disorders after stroke, which will expand the limits of cognitive rehabilitation. Using a novel brain imaging technique, called real-time functional magnetic resonance imaging (fMRI) neurofeedback combined with right hand motor imagery, this project will re-instate brain activity in the left language-dominant hemisphere. Stroke patients will practice modulating their own brain activity using fMRI neurofeedback signal and will select the most effective mental strategies that help them maintain brain activation patterns associated with better reading recovery.
Key facts
- Study ID
- NCT04875936
- Run by
- Kessler Foundation
- People needed
- 28
- Starts
- 2023-04-03
- Expected to finish
- 2027-06-30
- Last updated by the study team
- 2026-05-08
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- First-ever left-hemisphere stroke < 3 months prior to study recruitment or healthy volunteer
- Age: 18 - 80 years old
- Fluent and literate in English prior to stroke
- Reading deficits, defined as >3 errors on the Paragraphs test (subtests VIII, IX) of the Reading Comprehension Battery for Aphasia-2nd ed. (RCBA-2) in keeping with the healthy control accuracy criterion of 86-100% correct.
You may not qualify if…
- Inability to consent or complete study tasks
- Inability to undergo MRI (e.g., pregnancy, non-MRI compatible implants, claustrophobia)
- A history of prior neurological disease (e.g., brain tumor, Alzheimer's disease)
Where it is running
- Kessler Foundation — West Orange, New Jersey, United States (enrolling)
Full record on ClinicalTrials.gov
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