Complete Mesocolic Excision in Comparison With Conventional Surgery for the Right Colon Cancer

Recruiting now · Not applicable

Conditions studied: Colon Cancer

In brief

An Italian randomized controlled trial parallel-group in patients with a malignant tumor of the right or proximal transverse colon requiring right hemicolectomy.

Key facts

Study ID

NCT04871399

Run by

University of Turin, Italy

People needed

416

Starts

2020-07-13

Expected to finish

2027-01-01

Last updated by the study team

2022-11-14

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• American Society of Anesthesiologists(ASA) grade I-III.
• Right colon cancer (*The right-sided location of the cancer is defined as the location from the caecum up to the proximal third of the transverse colon), preoperative assessment of tumor stage T2-T4a, any N or T any N+ according to the National Comprehensive Cancer Network(NCCN) clinical practice guidelines in oncology: colon cancer version 2.2015); no distant metastasis.
• Informed consent

You may not qualify if…

• Age > 85 years old.
• T1, N0
• T4b, any N
• BMI > 30.
• Metastatic disease (Abdominal and chest CT scan will be mandatory to exclude distant metastasis.)
• American Society of Anesthesiologists(ASA) grade IV.
• History of cancer in recent 5 years.
• Need for Emergency surgery.
• Infectious disease requiring treatment.
• Pregnancy.
• Use of systemic steroids.
• No history of familial adenomatous polyposis, ulcerative colitis or Crohn's disease.

Where it is running

• University of Turin (AOU.San Luigi Gonzaga) — Torino, Italy (enrolling)
• Ospedale E. Agnelli Pinerolo — Pinerolo, Torino, Italy
• Maggiore Bellaria Hospital, Bologna — Bologna, Italy
• Università degli Studi di Ferrara — Ferrara, Italy
• Ospedale Policlinico San Martino — Genova, Italy
• Azienda Ospedaliera Universitaria Policlinico "G. Martino" — Messina, Italy
• European Institute of Oncology — Milan, Italy
• Federico II University — Naples, Italy
• University of Rome Tor Vergata — Rome, Italy
• Fondazione Policlinico Universitario Agostino Gemelli IRCCS — Rome, Italy
• Ospedale della Misericordia — Grosseto, Arezzo, Italy
• Ospedale Città di Sesto San Giovanni — Sesto San Giovanni, Milano, Italy
• Candiolo Cancer Institute - IRCCS — Candiolo, Torino, Italy
• S. Andrea Hospital — La Spezia, Spezia, Italy

Full record on ClinicalTrials.gov

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