A Study of LY3437943 in Participants With Type 2 Diabetes

Completed · Phase 2 · Has a placebo group

Conditions studied: Type 2 Diabetes

In brief

The main purpose of this study is to evaluate the efficacy and safety of LY3437943 in participants with type 2 diabetes (T2D) who failed to achieve adequate glycemic control on diet and exercise alone or on a stable dose of metformin. This study will last about 43 weeks.

Key facts

Study ID

NCT04867785

Run by

Eli Lilly and Company

People needed

281

Starts

2021-05-13

Expected to finish

2022-10-27

Last updated by the study team

2023-07-03

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Have Type 2 Diabetes (T2D)
• Have an HbA1c value at screening of ≥7.0% and ≤10.5% and treated with diet and exercise alone or with a stable dose of metformin (either immediate release or extended release, 1000 milligram (mg)/day and not more than the locally approved dose) for at least 3 months prior to screening.

You may not qualify if…

• Have type 1 diabetes mellitus (T1DM)
• Have ketoacidosis
• Have retinopathy, maculopathy
• Have history of pancreatitis
• Have obesity induced by other endocrine disorders
• Have uncontrolled hypertension
• Have acute or chronic hepatitis
• Have chronic kidney disease
• Have an autoimmune abnormality for example, lupus or rheumatoid arthritis
• Have an active or untreated malignancy

Where it is running

• Syed Research Consultants Llc — Sheffield, Alabama, United States
• San Fernando Valley Health Institute — Canoga Park, California, United States
• Valley Endocrine, Fresno — Fresno, California, United States
• National Research Institute - Huntington Park — Huntington Park, California, United States
• Catalina Research Institute, LLC — Montclair, California, United States
• National Research Institute - Panorama City — Panorama City, California, United States
• Anderson Clinical Research — Redlands, California, United States
• Artemis Institute for Clinical Research — Riverside, California, United States
• Artemis Institute for Clinical Research — San Diego, California, United States
• National Research Institute (NRI) - Santa Ana — Santa Ana, California, United States
• Diablo Clinical Research, Inc. — Walnut Creek, California, United States
• South Florida Clinical Research Institute — Margate, Florida, United States
• ForCare Clinical Research — Tampa, Florida, United States
• Encore Medical Research - Weston — Weston, Florida, United States
• Elite Clinical Trials — Blackfoot, Idaho, United States
• Humphreys Diabetes Center — Boise, Idaho, United States
• Rocky Mountain Clinical Research — Idaho Falls, Idaho, United States
• Elite Clinical Trials — Rexburg, Idaho, United States
• Iowa Diabetes and Endocrinology Research Center — West Des Moines, Iowa, United States
• Cotton O'Neil Clinic — Topeka, Kansas, United States
• Centennial Medical Group — Elkridge, Maryland, United States
• MediSync Clinical Research — Petal, Mississippi, United States
• Clinvest Research LLC — Springfield, Missouri, United States
• Logan Health Research — Kalispell, Montana, United States
• Lillestol Research — Fargo, North Dakota, United States

Full record on ClinicalTrials.gov

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